Summary: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention.However, the utility of these models is questionable given the differences in ARV pharmacology between humans and macaques.Here, we report a model based on ex Vase vivo ARV exposure and the challenge of mucosa
High-fidelity numerical investigation on structural integrity of SFR fuel cladding during design basis events
A high-fidelity numerical analysis methodology was proposed for evaluating the fuel rod cladding integrity of a Prototype Gen IV Sodium Fast Reactor (PGSFR) Play Mat during normal operation and Design basis events (DBEs).The MARS-LMR code, system transient safety analysis code, was applied to analyze the DBEs.The results of the MARS-LMR code were u
Characteristics of the population employed in primer sector in Turkey
Activities related to the production of raw material like agriculture husbandry, forestry, fishery are called as primer activities.Especially people living in rural areas earn Western Reins their livings on primer activities, mainly agriculture.Rural planning is inevitable for providing rural development which has an important place in all developm
An immunological autobiography: my year as a COVID-19 vaccine trial participant
After enrolling in the Moderna phase III clinical trial, I Western Reins collected my own biological samples pre- and post-immunization in the event of being a recipient of the experimental vaccine.The evidence strongly supports the conclusion that I did not receive the placebo.The analysis is admittedly limited to an n of 1, but the results fit we